What are SARMs?
SARM stands for Selective Androgen Receptor Modulator. Which to most people (unless you’re a scientist) still doesn’t tell you much!
What is an Androgen?
An Androgen is a class of hormones that serve as ligands that bind to cellular androgen receptors. All anabolic steroids or prohormones build muscle through binding to androgen receptors.
What is a selective modulator?
A receptor modulator is a compound that can block or stimulate the nuclear hormone receptor under different conditions. If it can successfully stimulate a receptor in a tissue selectively, it may be able to mimic the beneficial effects within that singular tissue and minimise the unwanted effects (side effects) of hormones within the other tissues. In the most basic terms, they can help build muscle and minimize side effects by focusing on only the targeted receptors.
SARMS essentially are intended to produce similar effects to that of androgenic drugs such as testosterone but would be much more selective in their action, allowing them to potentially have more uses in pharmaceuticals and cause less side effects than other anabolic products for performance enhancement purposes.
SARMs are agonists of the androgen receptor (AR) in anabolic tissues such as bone and skeletal muscle, but only partial agonists in androgenic areas such as the prostate and sex organs. Because of this they have a significantly higher separation of anabolic and androgenic effect. No estrogen conversion takes place and there is minimal spillover with other hormones. Because of this SARMs can help replicate some of the effects of anabolic steroids both without side effects from androgenic activity such as male pattern baldness and prostate hypotrophy.
Because of this SARMs may be highly effective for muscle wasting conditions such as osteoporosis, AIDS and cancer related wasting (cachexia).
Are SARMs safe?
In short, it depends who you ask. Hundreds of thousands of users across the world report results with minimal or no side effects from several different SARMs. But a smaller minority of users have experienced some side effects which vary from person to person as everyone is different.
If you have any pre-existing medical conditions you should not even consider SARMs, just in case. You should also be careful with ALL products that enter your body as you only have one life, so make sure it’s a healthy one.
If you are worried about the safety of SARMs or their side effects do your own research, read scientific studies, read a whole host of articles from all different sources so you can use your logic and common sense to evaluate risks and benefits for yourself. Bodybuilding Forums can also be a great place for some fantastic information; however, they can also be a terrible place for some hilarious fiction based off a legitimate study
SARMs vs Steroids?
SARMs popularity has exploded due to people promoting them as steroids without the side effects, or at least, fewer side effects. Who wouldn’t want steroid like results with none of the nasties right?
What are the considered benefits of SARMs over illegal steroids?
- All SARMs are taken orally and therefore no injections are needed.
- Compared to tablet or capsule steroids SARMs are not methylated and therefore, not toxic to the liver.
- No or very little conversion to estrogen.
- No or very little conversion to Dihydrotestosterone (DHT).
- Promote and Maintain Lean Muscle Growth
- Better Strength Gains
- Quicker Fat Loss
- Improved Athletic Performance
It is worth mentioning that taking SARMs is NOT as effective as steroids. If they were then everyone using steroids would have stopped and switched a long time ago. Having said this, SARMs are taken at a much lower dosage than steroids/testosterone. A typical Ostarine dosage is 20mg for 8 weeks but a typical 8-week testosterone dosage would be anywhere between 500-1000mg per week, so if Ostarine was taken at a similar dosage would similar testosterone results occur? Who knows? (no one is stupid enough to try this) But it is highly likely that the side effects at this dosage would probably be the same or worse than testosterone.
SARMs work much in the same manner as steroids. Meaning, they interact with androgen receptors to start producing more muscles. But, because they are selective, they don’t throw in a whole bunch of signals to the brain.
They work ‘selectively’ which makes them safer alternatives; something gym lovers and bodybuilders has been long waiting for.
What is the detection time for SARMs?
If you are asking this question, you probably shouldn’t be using SARMs, Just saying.
Drug testing for SARMs is now common practice in sports but was not up to as late as 2016. The detection times vary from SARM to SARM. Ostarine has a half-life of 24 hours or 23.8 hours to be exact however no study can be found that definitively shows the detection time. As an educated guess, it probably would be out of someone’s system within 12-weeks and after a detox.