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SARMs were created by accident. In the early Nineties, a scientist named Professor James T Dalton was working on pioneering treatments for prostate cancer when he identified the molecule Andarine – the first SARM.

It was of little use in treating prostate cancer, but it had a remarkable effect on muscle growth. In addition, from this discovery came many others product in relation to Sarms.

Sarms are Selective androgen receptor modulator they are anabolic compounds that bind to androgen receptors. They have been studied as potential treatments for cancer, osteoporosis, sexual dysfunction, multiple sclerosis, Alzheimer’s disease, and muscle wasting.

Recently, SARMs have been placed in various supplements marketed to fitness enthusiasts. Drug companies developed SARMs, which stands for selective androgen receptor modulators, as an alternative to anabolic steroids for people who suffer from age and disease-related muscle loss.

Recreational users of SARMs may take them in combination with each other on a cyclical basis.

Many athletes and gym-goers are turning to a popular but potentially dangerous new pill to help them build muscle and gain strength: a steroid alternative known as SARMs.

The pills are widely marketed online as “legal steroids” that provide the muscle-building benefits of anabolic steroids without the troubling side effects.

SARMs were designed to selectively target skeletal muscle and spare other tissues, in an attempt to reduce some of these unwanted side effects.

Androgen receptors are found all over the body – muscle, bone, prostate, secondary sexual organs and seminal vesicles. However, in bodybuilding terms, the only part that we really want to see effects of size, mass and strength on is the muscles.

Under normal circumstances, the body carefully regulates its androgen production through feedback mechanisms to prevent imbalances. Taking any form of anabolic steroid, SARM or estrogen modulator disrupts this natural mechanism in a good or bad way.

The main androgen modulators that athletes used are found in the form of “anabolic steroids”. These are known to increase muscle mass, growth and strength.

Most of the SARMS that have been developed so far are sought to overcome the potential virilisation and/or aromitisatizing effects of steroidal androgens. This was achieved by searching for tissue selective agonists of the AR that could potentially active the AR in specific tissues whilst sparing others.

The SARMS currently developed are non-steroidal, which means they are not susceptible to the enzymatic metabolism of target tissues. Remember, there were certain enzymes that converted DHT into metabolites, or synthesised testosterone from the precursor androstenedione, SARMS are not affected by these enzymes. This means that the SARMS do not convert or break down into the unwanted molecules that cause side effects, like DHT and estrogen.

The anabolic-to-androgenic ratio of steroids is 1:1. That is, you get the muscle building the same effect as you may get man boobs for example. This is where SARMS can come into play. They are more selective in boosting the anabolic effects of muscle building rather than causing the androgenic side effects. This ratio can start as little as 3:1 or go as high as 10:1.

SARMS are a group of synthetic drugs that mimic the effects of testosterone in muscle and bone with minimal impact on other organs and reduced side effects COMPARED to that of anabolic agents. The theory therefore is that you can have the benefits of steroids without the side effects.

What are the best SARMs to take?

  1. Ostarine MK-2866 (best SARM overall)

Ostarine has the most human research of any SARM. It is incredibly versatile, whether cutting or bulking, and side effects are very mild at low-moderate doses when used sensibly. If you have never used any SARMs before, this would be our first choice.

  1. Andarine S4 (best choice for women)

Andarine is a relatively mild SARM that is one of the better choices for women. Also known as S4, it can support gains in lean mass and recomp.

  1. Anabolic LGD-4033 (great for bulking)

Ligandrol is considered to be 11x stronger than ostarine, helping you gain muscle and size in a short amount of time. The perfect step up for anyone on a massing phase.

  1. Test Booster Rad-140 Testolone 

Testolone Rad-140, is one of the most popular SARMs. It is loved for its benefits to performance, recovery and allowing you to gain muscle at an enhanced rate.

  1. Myostatine YK-11 (the strongest SARM)

If you have been using SARMs for some time, and have experimented with the above options and stacking, YK-11 bridges the gap between SARMs and Prohormones. An incredibly strong SARM, always use with comprehensive cycle support and keep duration of use as short as possible.

  1. GH Booster MK677 Ibutamoren

Not a SARM but a GH-Secretagogue, Iburamoren (MK-677) has a powerful appetite increasing effect and can help sleep and recovery through increasing growth hormone. Perfect for stacking while on a bulk.

  1. Cardarine GW501516

Cardarine GW501516 is the second compound on this list that is not actually a SARM. Cardarine works via the PPAR pathway to increase endurance promote a healthy lipid profile and support fat loss.

8- Shred SR9009

Stenabolic SR9009 is superior to every other product for cutting. It is great at booing stamina and strength and it boosts your resting metabolism.

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